منابع مشابه
Biosynthesis of Gossypol
Based on the previous observations that gossypol is biosynthetically formed from acetate, and from the location of the incorporated 1% atoms, gossypol biosynthesis via the isoprenoid pathway has been postulated. To support this hypothesis, the incorporation of mevalonate-2J4C (a key intermediate in the isoprenoid pathway) into gossypol as well as the distribution of the radioactivity in the gos...
متن کاملGossypol biosynthesis in cotton revealed through
21 Gossypol plays an important role in defense mechanism of Gossypium species and the 22 presence of gossypol also limits the utilization of cottonseeds. However, little is 23 known about the metabolism of gossypol in cotton plant. Here, Detection on the 24 dynamic tendency of gossypol content illustrated that at the germination stage, the 25 main source of gossypol was cotyledon, and at the la...
متن کاملSpodoptera exigua modulates gossypol biosynthesis in cotton Gossypium hirsutum
Cotton plants induce high levels of gossypol in response to herbivore damage. However, little is known about the mechanisms by which insect herbivory modulates gossypol biosynthesis in cotton plants. Here, we report the mechanism by which herbivore damage or insect-originated elicitors modulate the biosynthesis of gossypol and jasmonic acid (JA) in plants. Spodoptera exigua larval-damaged (HD) ...
متن کاملGossypol inhibition of adenylate cyclase.
Gossypol, a polyphenolic binaphthalene -dialdehyde reputed to exert contraceptive action in males, reversibly inhibits adenylate cyclase [ATP pyrophosphate lyase (cyclizing), EC 4.6.1.1] in a concentration-dependent manner. In membranes prepared from a variety of organs, the half-maximal inhibitory concentration (IC50) ranges from 75 microM (rat Leydig tumor cells) to 250 microM (rat liver memb...
متن کاملGossypol Toxicity from Cottonseed Products
Gossypol is a phenolic compound produced by pigment glands in cotton stems, leaves, seeds, and flower buds (Gossypium spp.). Cottonseed meal is a by-product of cotton that is used for animal feeding because it is rich in oil and proteins. However, gossypol toxicity limits cottonseed use in animal feed. High concentrations of free gossypol may be responsible for acute clinical signs of gossypol ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1970
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)62845-5